Agenda

March 20, 2024

8:45 Structure of the Symposium: Max O’Donnell

8:55 Welcome to Columbia and Harlem: Wafaa El-Sadr

9:10 Greeting Symposium Attendees: Max O’Donnell and Barun Mathema

9:20 Kogieleum Naidoo: Introduction

9:30 Norbert Ndjeka: New drugs for drug-resistant TB in a high TB burden setting: Leadership, opportunities and the challenges of emerging drug resistance in South Africa

10:00 Kelly Dooley: The Tuberculosis Drug Development Pipeline – Harnessing Current (& Future) Knowledge to Address Highly Drug-Resistant TB

10:45 Tenzin Kunor: The importance of TB-affected community narratives and experiences in framing the challenges

11:00 Timothy Walker: Molecular tools for diagnosing drug resistance: where have we got to?

11:15 Amrita Daftary: Social dimensions of drug-resistant TB

11:30 David Dowdy: Emergence of resistance to BDQ: considerations from a modeling perspective

1:30 Viewpoints and Controversies in New Treatment Regimens
Chair:
Robert Horsburgh

Panel Members:
Puneet Dewan
Ma. Tarcela S. Gler
Michelle Larsen
Carole Mitnick
Paran Sarimita Winarni
Morten Ruhwald

2:45 Community and TB Champions Perspectives on Emerging Resistance
Chairs:
Jonathan Stillo, Amrita Daftary

Panel Members:
Stephen Anguva Shikoli
Phumeza Tisile
Paran Sarimita Winarni
Sachin Atre
Joe Burzynski
Marian Loveday

4:15 Diana Stanley: Publishing TB research: The best science for better lives

4:30 New TB Trials/Therapeutic Pipeline, New Regimens
Chairs: Neel Gandhi, Kelly Dooley

Panel Members:
Mel Spigelman
Molly Franke
Lindsay Mckenna
Tim Walker
Christopher Cousins

5:30 Closing Remarks: Salim Abdool Karim

March 21st, 2024

8:45 Robert Horsburgh: Opportunities for Prevention of TB Drug Resistance

9:00 Eric Nuermberger: Insights from murine model on new regimens

9:15 Uma Devi Ranganthan: Effectiveness and Safety of varying Doses of Linezolid with Bedaquiline and Pretomanid in Adults with Pre-Extensively Drug-Resistant Pulmonary Tuberculosis: Preliminary report

9:30 Gunar Günther: Evolving Bedaquiline resistance in the field – example from Namibia

Short Presentations

10:10 Debrah Vambe: Integration of targeted sequencing into national diagnostic and treatment algorithm in Eswatini

10:20 Phumeza Tisile: Insights from a TB Champion on South Africa's TB Policies

10:30 Boitumelo Seepamore: Adherence support interventions for key MDR-TB HIV infected populations

11:00 Morten Ruhwald Designing molecular diagnostics for current tuberculosis drug regimens

11:10 Helen Jenkins: Risk of emergence of rifampicin-resistance after loss to follow-up from tuberculosis treatment

11:20 Salome Charalambous: Digital Adherence tools for TB – experience from TB Mate and ASCENT projects

11:30 David Branigan: What is needed to realize universal access to TB drug-susceptibility testing as a human right?

11:40 Jennifer Furin: Prioritizing Person-Centered Tuberculosis Care: Urgent Actions to Combat Drug-Resistance

11:50 Dorothy Yeboah-Manu: Insights into drug resistance TB in Ghana, West Africa

1:00 Early Career Scientist Research Presentations 1
Chairs: Carole Mitnick, Dorothy Yeboah-Manu

Presenters:
Karl Reis
James Millard
Esmerelda Reyes
Noriah Maraba
Jonathan Stillo

1:00 Early Career Scientist Research Presentations 2
Chairs:
Luke Davis, Kelly Dooley

Presenters:
Kathleen Walsh
Camus Nimmo
Allison Wolf
Saranathan Rajagopalan
Dessa Casalme

2:00 Prevention of MDR-TB /Pediatrics
Chair: Yael Hirsch-Moverman

Panel Members:
Salome Charalambous
Paran Sarimita Winarni
Marian Loveday
Rovina Ruslami

2:00 Molecular basis of resistance to the new drugs
Chair: Michelle Larsen

Panel Members:
Camus Nimmo
James Millard
Uma Devi Ramalingam
Timothy Walker